Sunday 21 October 2012

Postdoctoral fellow position available

Date: 9 October 2012 15:37



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Job Available:
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Postdoctoral Fellowship Position in Biochemistry/Structural Biology

The research group of Yunsun Nam, Ph.D. at UT Southwestern Medical Center is seeking a postdoctoral fellow with expertise in protein biochemistry. The laboratory is housed in a newly renovated space at the heart of the Cecil H. and Ida Green Center. The overarching goal of our group is to elucidate the mechanistic details of RNA-regulated gene expression. We are particularly interested in the gene regulation pathways relevant to mammalian development and cancer.

Postdoctoral fellows will have many opportunities to learn the newest methods in biochemistry and biophysics, in addition to working in an exciting, fast evolving area in the field of biological and biomedical sciences. We use various approaches, including X-ray crystallography, NMR spectroscopy, molecular biology, nucleic acid and protein biochemistry, high throughput sequencing, and eukaryotic cell-based studies. For more information, please refer to the lab website: www.ynamlab.org   

Candidates must have a Ph.D. degree and a strong background in molecular biology and protein or nucleic acid biochemistry. Experience in structural biology is preferred. Interested individuals must submit a CV including contact information for 3 references, as a single pdf file to: Yunsun.Nam AT UTSouthwestern.edu


 *UT Southwestern is an Equal Opportunity/Affirmative Action Employer.


Tuesday 9 October 2012

Postdoctoral Position at ICR, London, UK


From: Sebastian Guettler
Date: 30 September 2012 10:40

Dear CCP4 Community,

We are currently looking for a postdoctoral fellow to join our new, exciting research programme on the regulation and functions of ADP-ribosyltransferases. Please see the job description for the position and instructions on how to apply below.

Best wishes,
Sebastian



Postdoctoral Position at ICR, London, UK

We seek to appoint a Post-doctoral Training Fellow to the Divisions of Structural and Cancer Biology of the Institute of Cancer Research (ICR; http://www.icr.ac.uk) in London, UK, to a new team led by Dr. Sebastian Guettler. The successful applicant will undertake biochemical, crystallographic and functional studies on members of the ADP-ribosyltransferase (or "PARP") family of proteins and their regulators. Our goal is to gain insight into the control and cellular roles of these enzymes with a specific interest in ADP-ribosyltransferase-dependent signalling processes linked to cancer.

Research in the Divisions of Structural and Cancer Biology focuses on the functional, biochemical, and structural characterisation of cellular processes relevant to cancer and cancer therapy. The Division of Structural Biology, where the laboratory will be physically based, has managed facilities for protein crystallography (crystallisation robots, Bruker Microstar and CCD detector), cryo-electron microscopy (FEI Tecnai F20 and T12), and protein production with expertise in multi-subunit expression (insect cell, yeast and bacterial expression, including a 60-litre fermentor). The Division is also well equipped with instrumentation for biophysical analysis (e.g. ITC, fluorescence, multi-angle light scattering). The Division of Cancer Biology provides a state-of-the-art infrastructure for mammalian cell culture, imaging, mammalian genetics, chemical biology and proteomics.

Applicants should possess a PhD (or equivalent) in biochemistry or molecular biology and a sound knowledge of protein purification for structural analyses. Experience with recombinant DNA techniques, protein expression and purification as well as protein crystallography is essential. Experience in mammalian cell culture, enzymology or protein production in insect cells (MultiBac) would be of advantage.

Length of contract: 3 years in the first instance
Salary range: £27,536 to £33,852 p.a. inclusive (depending on previous post-doctoral experience)
Closing date: 17th of October 2012
Starting date of position: earliest in November 2012

For further details and instructions on how to apply, please refer to our online vacancy and recruitment site at http://www.icr.ac.uk/jobsearch, quoting job reference number 1257974 for this position.

While applications need to be placed via our online system, informal inquiries can be sent to Dr. Sebastian Guettler at sebastian.guettler@icr.ac.uk.

The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP.

This e-mail message is confidential and for use by the addressee only.  If the message is received by anyone other than the addressee, please return the message to the sender by replying to it and then delete the message from your computer and network.

Job opening at the Austrian Centre of Industrial Biotechnology

From: Karl Gruber
Date: 29 September 2012 20:08


For an ongoing project on enzyme design and development we are looking for a computational scientist with a keen interest in structural biology or a structural biologist with a strong background in informatics and computer programming.

Details can be found at:

http://www.acib.at/index.php/wbNews/detail/110

Wednesday 3 October 2012

Professor Dame Louise Johnson

From: <elizabeth.duke


It is with great sadness that I would like to inform the crystallographic community of the death of one of the great pioneers of the field, Professor Dame Louise Johnson.

 

Those of us who had the privilege to work alongside her benefitted greatly from her vision for extending technique and instrumentation such that increasingly complex problems could be successfully solved and found her quiet determination to succeed inspirational.

 


 


 

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From: Gloria Borgstahl k


This indeed is sad news for today. 
I just wanted to note that Professor Johnson's early papers on time-resolved crystallography truly inspired me to continue in crystallography, influenced my decision for my first postdoctoral position and to push the limits.  I still have the carefully highlighted photocopies (yes used a photocopier and a real bound journal in gradual school) in my filing cabinet next to my office.
 
My condolences to those close to her and her family.  Gloria


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From: Laurie Betts

What a great lady to have inspired so many, and to remind us how welcoming the field of X-ray crystallography has been in general for women because of people like Dr. Johnson, Dorothy Hodgkin, and Rosalind Franklin, and many others. 

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From: Felix Frolow


As a devoted reader of the "Protein Crystallography" - the first and only comprehensive manual of the protein crystallography,
I express my deep sorrow on the departure from us of  DBE Commander, Professor Louise Johnson.
May her soul rest in peace. 
In full honor,

Dr Felix Frolow   


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From: vellieux


A very nice picture of Prof. Louise Johnson can be found on

http://www.flickr.com/photos/wellcomeimages/5814718414/

The picture was taken at Diamond's IO2 beam line.

Condolences to her family and friends.

Fred.

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From: Enrico Stura


Professor Dame Louise Johnson was my thesis supervisor and I am saddened by
her departure.

I would like to encourage the crystallographic community to contribute to:
http://en.wikipedia.org/wiki/Louise_Johnson
so that her achievemens can be remenbered and can continue to inspire
future generations of crystallographers.

Those that have access to a copyright -free photograph can upload it to Wikipedia Commons:
http://commons.wikimedia.org/wiki/Main_Page

I would like to extend my condolences her family and all her friends.

Enrico.