Post-doctoral position in Lyon, France

From: Laurent Terradot
Date: 28 August 2012 12:36

Post-doctoral position in Structural Biology of Bacterial Pathogenesis at the IBCP (Lyon, France)

 

A FINOVI (http://www.finovi.org) funded postdoctoral position is available immediately in the group of Laurent Terradot at the Institut de Biologie et Chimie des Protéines (IBCP), Lyon, (http://www.ibcp.fr). We are interested in the structure/function of protein complexes involved in bacterial pathogenesis. The funded position will aim to solve the structures of type IV secretion system effectors and understand their mode(s) of action (see Tosi et al., Febs L, 2009; Jimenez-Soto et al., PloS Pathogens, 2009; Kaplan-Türköz et al., PNAS, 2012). The project is a collaboration between our laboratory and team of P. Doublet at the University of Lyon 1.

 

The IBCP is well equipped for Molecular Biology, Biochemistry, Bioinformatics and Structural Biology and belongs to a larger campus (UMS3444/US8, Lyon Biopole; Center for Infectiology), giving access to state-of-the-art core facilities, including crystallogenesis and biophysics platforms. The group has regular access to synchrotron beam time and is ideally located one hour from the European Synchrotron ESRF. Lyon is a vibrant, historical French city and is a world-excellence center in Infectiology.

 

We are looking for enthusiastic and self-motivated individuals with a strong background in X-ray crystallography, model building and refinement. Successful experience in protein purification for structural studies is required. Experience in protein-protein interactions (Biacore, ITC) and/or study of large complexes would be a plus. Working language of the laboratory is English.

 

Starting date: As soon as possible.

Salary is according to the CNRS french guidelines.

Please send a cover letter, your CV and reference letters as a single PDF file to: laurent.terradot@ibcp.fr

 

Address:

 

Laurent Terradot

 

Institut de Biologie et Chimie des Protéines

ATIP-CNRS Group Structural Biology of Bacterial Macromolecular Complexes

UMR 5086 CNRS Université de Lyon

7, passage du Vercors

69367 Lyon cedex 07 FRANCE