From: Wei Shi
Date: 19 November 2011 20:44
Hi all,
I want to change a piece of DNA in pdb file to match the target DNA sequence in order to be used as a search model in molecular replacement. Does anyone happen to know how I could do this? Thank you so much!
Best,
Wei
----------
From: Tim Gruene
Dear Wei,
you could use coot "Calculate->Model/Fit/Refine->Simple Mutate" also for
nucleic acids.
It may be worth running geometry idealisation in coot or refmac5 before
using the model in MR.
Tim
- --
- --
Dr Tim Gruene
Institut fuer anorganische Chemie
Tammannstr. 4
D-37077 Goettingen
Date: 19 November 2011 20:44
Hi all,
I want to change a piece of DNA in pdb file to match the target DNA sequence in order to be used as a search model in molecular replacement. Does anyone happen to know how I could do this? Thank you so much!
Best,
Wei
----------
From: Tim Gruene
Dear Wei,
you could use coot "Calculate->Model/Fit/Refine->Simple Mutate" also for
nucleic acids.
It may be worth running geometry idealisation in coot or refmac5 before
using the model in MR.
Tim
- --
- --
Dr Tim Gruene
Institut fuer anorganische Chemie
Tammannstr. 4
D-37077 Goettingen
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