Tuesday, 27 September 2011

Employment Res Assoc/ Postdocs KU-Pharm and Tox

We are seeking highly motivated individuals to fill in Research Associate and Postdoctoral positions to study the structure and function of proteins involved in lipid metabolism or lipid signaling by means of X-ray crystallography in the laboratory of Dr. Alex Moise at the Department of Pharmacology and Toxicology, School of Pharmacy, University of Kansas http://midwestlipids.com. The positions are funded by NIH. The laboratory is well equipped to analyze lipid metabolism and study lipid signaling, cell and animal models with altered lipid signaling and to conduct protein expression and purification. Our funding and project oversight is from the KU COBRE Center in Protein Structure and Function http://psf.cobre.ku.edu/ which provides core services in protein purification, reagents and setup for crystallization screening, diffraction and structure determination by X-ray and NMR and use of equipment including a Rigaku RU-H3RHB X-ray generator with an R-axis IV++ imaging plate system, a Bruker Avance 800 MHz NMR instrument fitted with a TCI cryoprobe and a Bruker Avance III 600 MHz with a variety of probes, Biacore for label free studies. KU campus also hosts a High Throughput Screening Laboratory, a Center for Bioinfomatics and a Mass Spectrometry facility.  In addition, through our collaborators Scott Lovell and Kevin Battaile, we have regular access to synchrotron radiation beamlines at Argonne National Labs IMCA-CAT 17. The environment is excellent and there is a lot of good work to be done.

Successful candidates must have a Ph.D. in biochemistry or a related field with a strong background in purification of proteins, protein-ligand complexes and the use of structural methods to investigate enzyme mechanism and to develop modulators. A background in membrane protein purification or purification of lipid processing enzymes is preferred. For more information email alexmoise@ku.edu. Review of applications will begin shortly and will continue until the positions are filled. Salary will be commensurate with experience. If a candidate has more than five years post PhD than the candidate will be automatically considered for a Research Position as per HR. University of Kansas is an EO/AA Employer.

In 2011, KU School of Pharmacy ranked fourth in the nation among Schools of Pharmacy in the amount of National Institutes of Health funding; 2011 is the 10th consecutive year the school has been ranked in the top five receiving more than $18,400,000 in NIH research funding in fiscal year 2010. The KU School of Pharmacy is situated in Lawrence Kansas, which was named one of the top 10 US college towns along with Austin TX, Boulder CO, Madison WI, and Berkeley CA  by Parents &Colleges and also made the list of top college towns by the American Institute for Economic Research, MSN and MSNBC. Lawrence boasts a vibrant downtown, youthful attitude - nearly 50% of residents are younger than 24 years of age - and a multitude of outdoor activities at Clinton Lake, the Kansas River and the city's 50 parks. Kansas City, a 41 miles east of Lawrence is a major US city with a variety of renowned museums, athletic venues, dining and cultural institutions.

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