Tuesday, 10 April 2012

Proteins that require membrane to be folded


From: Katya Heldwein
Date: 21 March 2012 12:59


Dear CCP4BB community,

Does anyone know of proteins (or protein domains) that are better folded in the presence of a membrane or a membrane mimetic (higher secondary structure content, stability, etc.)? I am interested in peripheral membrane proteins or extra/intracellular domains of membrane-anchored proteins, particularly, cases where the structural basis for the membrane requirement is understood.

Sincerely,

Katya Heldwein, Ph.D.


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