Open position at Bristol-Myers Squibb (Princeton, NJ, USA) Third time is the charm?

Date: 4 January 2012 19:33

 

 

RESEARCH INVESTIGATOR I-1105118

Job Description

• As a key member of the Protein Science and Structures team, the successful candidate will be responsible for purification, characterization, and crystallization of recombinant proteins utilizing knowledge of conventional and affinity chromatography methods, gel electrophoresis, crystallization, and general laboratory procedures.
• As a member of a team involved in the early stages of discovery, the position requires close collaboration with molecular biologists and structural biologists as well as scientists working in the various disease biology and translational areas within preclinical research.
• The candidate must be self-motivated, possess good communication skills, and work both independently as well as in teams.
• Personal attributes of integrity and scientific creativity are required.

Qualifications

• The successful candidate is required to have experience in protein crystallization, harvesting, and data collection.
• The candidate should also be familiar with the methods of determining protein X-ray structures including indexing/scaling of data, structure determination through molecular replacement and other techniques, refinement, and analysis of the resulting structure.
• The candidate is also required to have experience in protein purification / characterization as well as a thorough understanding of protein chromatography principles.
• Demonstrated ability to devise and implement novel multi-step purification using protein chromatography workstations is sought (e.g. AKTA Purifier/Explorer, gel filtration, ion exchange chromatography, microfiltration, and other related techniques) as applied to materials from microbial and eukaryotic expression sources (secreted & inclusion bodies).
• Capable of independently designing experiments, generating data and interpreting results; demonstrated ability to work in a team environment. Good listener. Strong, concise, and consistent written and oral communication required.
• Ability to independently troubleshoot HPLC and other purification systems and protocols a plus.
• Experience in E coli fermentation / protein expression a plus.

PH.D. in Biochemistry, Structural Biology, or related field. 0-5 years experience.

Apply online to this position.

 

N.B. You will receive a confirmation email after successfully completing the online application.