Postdoctoral position in Oxford Biochemistry

Date: 25 January 2012 13:15


Dear all,

A postdoctoral position is available in Oxford Biochemistry for combined
crystallographic and NMR studies of centriolar proteins. The advert is
below and applications can be made online until Feb. 20th.

Regards,

John Vakonakis





                         UNIVERSITY OF OXFORD


                      DEPARTMENT OF BIOCHEMISTRY


        Postdoctoral Research Associate in Structural Biology


We are seeking to appoint a highly motivated Postdoctoral Research
Associate in the laboratory of Dr. Ioannis Vakonakis for studies of
proteins involved in centriole assembly. The successful candidate will
join a multidisciplinary collaboration between Oxford and the groups of
Prof. Pierre Gönczy (EPFL) and Dr. Michel Steinmetz (Paul Scherrer
Institute) in Switzerland. Recently, our joint efforts elucidated the
origins of centriolar 9-fold symmetry (Kitagawa, Vakonakis et
al.,Cell144, 364-375, 2011), a critical step in the centrosomal
duplication process that ensures genome stability in animals. We now
seek to build upon this breakthrough by studying the structure/function
relationship of centriolar components such as SAS-6, SAS-5, SAS-4,
ZYG-1, SPD-2 and others. The successful candidate will contribute to the
analysis of these targets using structural (crystallography, solution
NMR and/or small angle scattering) and biophysical methods.


Applicants should possess/be expected to obtain a PhD in natural
sciences and should have experience in aspects of the structural biology
pipeline, for example protein production and purification, NMR
spectroscopy or X-ray crystallography. Past experience with
complementary biophysical techniques (ITC, AUC, CD etc) and biomolecular
interactions is desirable. Previous familiarity with centriolar or
relevant biological systems would be an advantage but is not essential.


This full-time post is funded by the Biotechnology and Biological
Sciences Research Council (BBSRC)for up to three years in the first
instance and is based in the New Biochemistry building, South Parks
Road, Oxford. More information about our group can be found by clicking
on the link below:


http://www2.bioch.ox.ac.uk/~rrnmr


This position is graded on the University's grade 7 scale, for which the
salary range is £29,099 - £35,788 per annum. The actual starting salary
offered will be based on qualifications and relevant skills acquired and
will also be determined by the funding available.


For further general information, phone (01865) 613204, quoting reference
number BR/493.


Applications for this vacancy are to be made online.


To apply for this role and for further details, including the job
description and selection criteria,

please click on the link below:


https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=101979


The closing date for applications is Monday, 20thFebruary 2012. It is
envisioned that interviews for shortlisted candidates will take place
within approximately 10-14 days.


The University of Oxford is committed to equality and values diversity.